A Concise Review of Molecular Pathology of Breast Cancer

InTAvE | 2015 | ISBN: 9535120301 9789535120308 | 233 Pages | PDF | 6 MB

This book discusses gene expression and DNA abnormalities including methylation in breast cancer. A recent important topic, roles of miRNAs and their potential use in cancer therapy have been discussed in this cancer type as well.

Cancer is one of the leading causes of death in most countries and its consequences result in huge economic, social and psychological burden. Breast cancer is the most frequently diagnosed cancer type and the leading cause of cancer death among females.
Bioinformatics is very important part of recent human genome developments and data mining and thus this topic has also been added for the readers.
This book will contribute to development of novel diagnostic as well as therapeutic approaches, which lead to cure of breast cancer.

Contents
Preface
1 Breast Cancer - It's All in the DNA
2 DNA Methylation
3 Genome-Wide Gene Expression Analysis to Identify Epistatic Gene-Pairs Associated with Prognosis of Breast Cancer
4 MicroRNA in Breast Cancer - Gene Regulators and Targets for Novel Therapies
5 MicroRNAs as Therapeutic Targets in Human Breast Cancer
6 Plasminogen Activator System - Diagnostic, Prognostic and Therapeutic Implications in Breast Cancer
7 Bioinformatics in Breast Cancer Research
8 Relationship of Breast Cancer with Ovarian Cancer
9 Enantiomerically Pure Substituted Benzo-Fused Heterocycles - A New Class of Anti-Breast Cancer Agents
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