Adenosine Receptors and Parkinson's Disease

Stationary Office | Pages: 275 | 2000-01-15 | ISBN: 0124004059 | 15 MB | Rapidshare and Megaupload

This book is the first definitive overview on adenosine receptor antagonists and their application to the treatment of Parkinson's Disease. The effect of these novel non-dopamine drugs on vitro and in vivo systems clearly shows their potential for the treatment of this debilitating disease.

Key Features
* Discusses the discovery and development of a novel non-dopaminomimetic agent for Parkinson's disease
* Provides the first definitive overview of adenosine antagonists and their role in the treatment of Parkinson's disease
* Presents a new mechanism of action of adenosine A2A receptor antagonists in motor function
Proposes a hypothesis of adenosine A2A receptor function in the striatum
* Comprehensive overview of adenosine, its receptor subtypes, their antagonists/agonists from biochemistry, molecular biology, medicinal chemistry, physiology, pharmacology, and neurochemistry viewpoints

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