Advances in Food Research. Volume 22



Advances in Food Research. Volume 22
Publisher: Academic Press Inc.,U.S | ISBN 0120164221 | Pages: 373 | File type: PDF | 1976-07 | 19 mb
Although the qualitative behavior of many of these compounds is well known, it has not been possible to establish a dose-response relationship, and hence a no-response level, even in animal studies. Further problems arise in extrapolation of the results to the human situation, and in the large numbers of animals in both study and control groups which are necessary when operating at the low dosage levels required for the results to be statistically significant. Some of these problems have been discussed recently by Grasso (1973).

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